Protein Ontology Report - hMYD88 PR:Q99836 - http://purl.obolibrary.org/obo/PR_Q99836

This page represents a class of proteins encompassing all the protein products of the MYD88 gene in human .

Ontology Information
PRO ID	PR:Q99836 Show OBO stanza / PAF
PRO name	myeloid differentiation primary response protein MyD88 (human)
Synonyms	PRO-short-label: hMYD88 Gene-based: MYD88
Definition	A myeloid differentiation primary response protein MyD88 that is encoded in the genome of human. [PRO:CNA]
PRO Category	organism-gene
Parent	PR:000001740 myeloid differentiation primary response protein MyD88
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 8 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	HGNC:7562, Reactome:R-HSA-166059, Reactome:R-HSA-193946, Reactome:R-HSA-937017, Reactome:R-HSA-975123, UniProtKB:Q99836

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hMYD88 forms found in complexes

hMYD88 Component Complexes PR:000001740 MYD88 PR:000027182 IRAK4:MYD88:TIRAP:activated TLR4 complex PR:000001740 MYD88 PR:000025784 MYD88:TIRAP:activated TLR4 receptor PR:Q99836 hMYD88 PR:000037446 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (human) PR:Q99836-1 hMYD88/iso:1 PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human) PR:Q99836-1 hMYD88/iso:1 PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human) PR:Q99836-1 hMYD88/iso:1 PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000001740 MYD88 has_part Pfam:PF01582 TIR domain has_part Pfam:PF00531 Death domain PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human) participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human) participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human) participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 Biological Process GO Term Protein Forms & Complexes Evidence GO:0034142 toll-like receptor 4 signaling pathway PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human) Reactome:REACT_6894 PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human) Reactome:REACT_6894 PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human) Reactome:REACT_6894

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