iPTMnet Report for Q9Y512 (SAMM50)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y512 / SAM50_HUMAN
Protein Name Sorting and assembly machinery component 50 homolog
Gene Name Name: SAMM50
Synonyms:SAM50;ORFNames:CGI-51,TRG3;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y512
DAG View
PRO Name sorting and assembly machinery component 50 homolog (human)
Definition A sorting and assembly machinery component 50 that is encoded in the genome of human.
Short Label hSAMM50
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y512 (SAMM50) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K36 Ubiquitination PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
C65 S-Nitrosylation dbSNO 26338901
K72 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
S83 O-Glycosylation GlyGen 28411811, 28510447, 33465208, ...35254053
T160 O-Glycosylation GlyGen 33465208
S164 O-Glycosylation GlyGen 28411811, 28510447, 33465208, ...35254053
K178 Acetylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
S202 O-Glycosylation GlyGen 28411811, 28510447, 33465208, ...35254053
Y215 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
S250 O-Glycosylation GlyGen 28411811, 28510447, 33465208, ...35254053
K255 Methylation PhosphoSitePlus   UniProt 24129315
S269 Phosphorylation PhosphoSitePlus
S270 Phosphorylation HPRD   PhosphoSitePlus 20068231
K297 Acetylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S83 F83 Biomuta DOID:4159 / skin cancer [ cosmic ]
S164 F164 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y215 H215 Biomuta DOID:3571 / liver cancer [ cosmic ]
S239 L239 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S250 I250 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K297 * Biomuta DOID:4159 / skin cancer [ cosmic ]