Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y512 / SAM50_HUMAN
Protein Name Sorting and assembly machinery component 50 homolog
Gene Name Name: SAMM50
Synonyms:SAM50;ORFNames:CGI-51,TRG3;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y512
DAG View
PRO Name sorting and assembly machinery component 50 homolog (human)
Definition A sorting and assembly machinery component 50 that is encoded in the genome of human.
Short Label hSAMM50
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y512 (SAMM50) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K36 Ubiquitination PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
C65 S-Nitrosylation dbSNO 26338901
K72 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K178 Acetylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
K255 Methylation PhosphoSitePlus   UniProt 24129315
S269 Phosphorylation PhosphoSitePlus
S270 Phosphorylation HPRD   PhosphoSitePlus 20068231
K297 Acetylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S239 L239 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
S269 C269 Biomuta DOID:5041 / esophageal cancer [ tcga ]