iPTMnet Report for Q9Y4I1 (MYO5A)
Protein Information
| UniProt AC / UniProt ID | Q9Y4I1 / MYO5A_HUMAN |
| Protein Name | Unconventional myosin-Va |
| Gene Name | Name: MYO5A Synonyms:MYH12; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y4I1 |
| PRO Name | unconventional myosin-Va (human) |
| Definition | A myosin-Va that is encoded in the genome of human. |
| Short Label | hMYO5A |
| Category | organism-gene |
Q9Y4I1 (MYO5A) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S172 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| Y175 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K246 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S600 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19413330, 23186163, 19664995 | ||
| T610 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T615 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R623 | Methylation | score1 | PhosphoSitePlus | |||
| S721 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y757 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y828 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y834 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K902 | Acetylation | score1 | PhosphoSitePlus | |||
| Y918 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K979 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S987 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1028 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1032 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1050 | Methylation | score1 | PhosphoSitePlus | |||
| K1058 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1078 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1086 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1113 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1115 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983 | ||
| T1116 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983 | ||
| S1118 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1203 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1207 | Acetylation | score1 | PhosphoSitePlus | |||
| K1207 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1213 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 16097034 | ||
| K1232 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1312 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1339 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1400 | Phosphorylation | score0 | HPRD | 18452278 | ||
| T1409 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S1452 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20068231 | ||
| Y1511 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1531 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1534 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S1535 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1536 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1539 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1572 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C1589 | Methylation | score1 | IEDB | 31844290 | ||
| T1650 | Phosphorylation | score4 | HPRD neXtProt phospho.ELM PhosphoSitePlus | 18669648, 17515613 | ||
| T1650 | Phosphorylation | P31751 (AKT2) | score2 | neXtProt | 17515613 | |
| S1651 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1652 | Phosphorylation | score2 | HPRD phospho.ELM PRO PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| T1658 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
| T1743 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K1424 | Ubiquitination | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000048509 (hMYO5A/Phos:1) | pS1652 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y175 | C175 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] | |
| Y175 | D175 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| K246 | N246 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T610 | A610 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y757 | F757 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| Y834 | F834 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| T1032 | A1032 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K1058 | N1058 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K1058 | T1058 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S1213 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
| S1531 | L1531 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T1650 | S1650 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] |
DAG View