Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4I1 / MYO5A_HUMAN
Protein Name Unconventional myosin-Va
Gene Name Name: MYO5A
Synonyms:MYH12;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4I1
DAG View
PRO Name unconventional myosin-Va (human)
Definition A myosin-Va that is encoded in the genome of human.
Short Label hMYO5A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4I1 (MYO5A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K9 Ubiquitination PhosphoSitePlus
Y31 Phosphorylation PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
S172 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y175 Phosphorylation HPRD 20068231
S199 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
S600 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 19664995
T610 Phosphorylation PhosphoSitePlus
T615 Phosphorylation PhosphoSitePlus
R623 Methylation PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
Y757 Phosphorylation PhosphoSitePlus
Y828 Phosphorylation PhosphoSitePlus
Y834 Phosphorylation PhosphoSitePlus
K902 Acetylation PhosphoSitePlus
Y918 Phosphorylation PhosphoSitePlus
K979 Ubiquitination PhosphoSitePlus
S987 Phosphorylation PhosphoSitePlus
K1028 Ubiquitination PhosphoSitePlus
T1032 Phosphorylation PhosphoSitePlus
K1050 Methylation PhosphoSitePlus
K1058 Ubiquitination PhosphoSitePlus
Y1078 Phosphorylation PhosphoSitePlus
S1086 Phosphorylation PhosphoSitePlus
T1113 Phosphorylation PhosphoSitePlus
S1115 Phosphorylation HPRD   PhosphoSitePlus 17081983
T1116 Phosphorylation HPRD   PhosphoSitePlus 17081983
S1118 Phosphorylation PhosphoSitePlus
S1119 Phosphorylation PhosphoSitePlus
Y1203 Phosphorylation PhosphoSitePlus
S1205 Phosphorylation PhosphoSitePlus
K1207 Acetylation PhosphoSitePlus
K1207 Ubiquitination PhosphoSitePlus
S1213 Phosphorylation phospho.ELM   PhosphoSitePlus 16097034
K1232 Ubiquitination PhosphoSitePlus
Y1312 Phosphorylation PhosphoSitePlus
Y1339 Phosphorylation PhosphoSitePlus
S1400 Phosphorylation HPRD 18452278
T1409 Phosphorylation HPRD 18452278
S1452 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
Y1511 Phosphorylation PhosphoSitePlus
S1531 Phosphorylation PhosphoSitePlus
T1534 Phosphorylation HPRD   PhosphoSitePlus 20068231
S1535 Phosphorylation PhosphoSitePlus
T1536 Phosphorylation PhosphoSitePlus
S1539 Phosphorylation PhosphoSitePlus
S1572 Phosphorylation PhosphoSitePlus
T1650 Phosphorylation P31751 (AKT2) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 18669648, 17515613
S1651 Phosphorylation PhosphoSitePlus
S1652 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus   UniProt 18669648, 23186163
T1658 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T1743 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K1424 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048509 (hMYO5A/Phos:1) pS1652 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y175 D175 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
Y175 C175 Biomuta DOID:3571 / liver cancer [ tcga ]
K246 N246 Biomuta DOID:10534 / stomach cancer [ tcga ]
Y757 F757 Biomuta DOID:11934 / head and neck cancer [ tcga ]
Y834 F834 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T1032 A1032 Biomuta DOID:363 / uterine cancer [ tcga ]
K1058 N1058 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K1058 T1058 Biomuta DOID:363 / uterine cancer [ tcga ]
S1213 * Biomuta DOID:1612 / breast cancer [ cosmic, tcga ] DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
T1409 N1409 Biomuta DOID:3571 / liver cancer [ icgc ]
T1650 S1650 Biomuta DOID:3571 / liver cancer [ tcga ]