iPTMnet Report for Q9Y4I1 (MYO5A)
Protein Information
UniProt AC / UniProt ID | Q9Y4I1 / MYO5A_HUMAN |
Protein Name | Unconventional myosin-Va |
Gene Name | Name: MYO5A Synonyms:MYH12; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y4I1 |
PRO Name | unconventional myosin-Va (human) |
Definition | A myosin-Va that is encoded in the genome of human. |
Short Label | hMYO5A |
Category | organism-gene |
Q9Y4I1 (MYO5A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y31 | Phosphorylation | score1 | PhosphoSitePlus | |||
K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
S172 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
Y175 | Phosphorylation | score0 | HPRD | 20068231 | ||
S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
K246 | Ubiquitination | score1 | PhosphoSitePlus | |||
K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
S600 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19413330, 23186163, 19664995 | ||
T610 | Phosphorylation | score1 | PhosphoSitePlus | |||
T615 | Phosphorylation | score1 | PhosphoSitePlus | |||
R623 | Methylation | score1 | PhosphoSitePlus | |||
S721 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y757 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y828 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y834 | Phosphorylation | score1 | PhosphoSitePlus | |||
K902 | Acetylation | score1 | PhosphoSitePlus | |||
Y918 | Phosphorylation | score1 | PhosphoSitePlus | |||
K979 | Ubiquitination | score1 | PhosphoSitePlus | |||
S987 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1028 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1032 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1050 | Methylation | score1 | PhosphoSitePlus | |||
K1058 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1078 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1086 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1113 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1115 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983 | ||
T1116 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983 | ||
S1118 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1119 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1203 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1205 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1207 | Acetylation | score1 | PhosphoSitePlus | |||
K1207 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1213 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 16097034 | ||
K1232 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1312 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1339 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1400 | Phosphorylation | score0 | HPRD | 18452278 | ||
T1409 | Phosphorylation | score0 | HPRD | 18452278 | ||
S1452 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20068231 | ||
Y1511 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1531 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1534 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S1535 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1536 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1539 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1572 | Phosphorylation | score1 | PhosphoSitePlus | |||
C1589 | Methylation | score1 | IEDB | 31844290 | ||
T1650 | Phosphorylation | P31751 (AKT2) | score4 | HPRD neXtProt phospho.ELM PhosphoSitePlus | 18669648, 17515613 | |
S1651 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1652 | Phosphorylation | score2 | HPRD phospho.ELM PRO PhosphoSitePlus UniProt | 18669648, 23186163 | ||
T1658 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
T1743 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K1424 | Ubiquitination | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000048509 (hMYO5A/Phos:1) | pS1652 | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y175 | C175 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] | |
Y175 | D175 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
K246 | N246 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T610 | A610 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y757 | F757 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
Y834 | F834 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T1032 | A1032 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K1058 | N1058 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K1058 | T1058 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S1213 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
S1531 | L1531 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T1650 | S1650 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] |