iPTMnet Report for Q9Y3B2 (EXOSC1)
Protein Information
| UniProt AC / UniProt ID | Q9Y3B2 / EXOS1_HUMAN |
| Protein Name | Exosome complex component CSL4 |
| Gene Name | Name: EXOSC1 Synonyms:CSL4;ORFNames:CGI-108; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y3B2 |
| PRO Name | exosome complex component CSL4 (human) |
| Definition | An exosome complex component CSL4 that is encoded in the genome of human. |
| Short Label | hEXOSC1 |
| Category | organism-gene |
DAG ViewQ9Y3B2 (EXOSC1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| R6 | Methylation | score1 | PhosphoSitePlus | |||
| S21 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18691976, 18669648, 23186163, ... | ||
| Y27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C40 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y89 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S92 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S98 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K180 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y89 | H89 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |
