Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9Y3B2 / EXOS1_HUMAN
Protein Name Exosome complex component CSL4
Gene Name Name: EXOSC1
Organism Homo sapiens (Human)

DAG View
PRO Name exosome complex component CSL4 (human)
Definition An exosome complex component CSL4 that is encoded in the genome of human.
Short Label hEXOSC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9Y3B2 (EXOSC1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
R6 Methylation PhosphoSitePlus
S21 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
Y27 Phosphorylation PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
C40 S-Nitrosylation dbSNO 26338901
S44 Phosphorylation PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus   UniProt 23186163
K113 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
Y119 Phosphorylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y89 H89 Biomuta DOID:1612 / breast cancer [ cosmic ]