iPTMnet Report for Q9Y2X0 (MED16)
Protein Information
| UniProt AC / UniProt ID | Q9Y2X0 / MED16_HUMAN |
| Protein Name | Mediator of RNA polymerase II transcription subunit 16 |
| Gene Name | Name: MED16 Synonyms:DRIP92; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y2X0 |
| PRO Name | mediator of RNA polymerase II transcription subunit 16 (human) |
| Definition | A mediator of RNA polymerase II transcription subunit 16 that is encoded in the genome of human. |
| Short Label | hMED16 |
| Category | organism-gene |
DAG ViewQ9Y2X0 (MED16) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S53 | O-Glycosylation | score1 | GlyGen | 30379171, 34019948 | ||
| C86 | Methylation | score1 | IEDB | 31844290 | ||
| K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T257 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C308 | Methylation | score1 | IEDB | 31844290 | ||
| K313 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S326 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K332 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K338 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K358 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T364 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K530 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K535 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C539 | Methylation | score1 | IEDB | 31844290 | ||
| C545 | Methylation | score1 | IEDB | 31844290 | ||
| Y547 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T549 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T571 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K574 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C584 | Methylation | score1 | IEDB | 31844290 | ||
| K586 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T588 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K594 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C672 | Methylation | score1 | IEDB | 31844290 | ||
| T682 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S685 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S687 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T694 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K695 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K745 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T757 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K778 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K796 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K808 | Methylation | score1 | PhosphoSitePlus | |||
| K808 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K817 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S53 | G53 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| C584 | Y584 | Biomuta | DOID:11615 / penile cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
| K586 | E586 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T588 | I588 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K594 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S687 | Y687 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K695 | T695 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K778 | E778 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
