iPTMnet Report for Q9Y2R0 (COA3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2R0 / COA3_HUMAN
Protein Name Cytochrome c oxidase assembly factor 3 homolog, mitochondrial
Gene Name Name: COA3
Synonyms:CCDC56,MITRAC12;ORFNames:HSPC009;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2R0
DAG View
PRO Name cytochrome c oxidase assembly factor 3 homolog, mitochondrial (human)
Definition A coiled-coil domain-containing protein 56 that is encoded in the genome of human.
Short Label hCOA3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2R0 (COA3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
S12 Phosphorylation PhosphoSitePlus
R14 Methylation PhosphoSitePlus
T26 Phosphorylation HPRD 20068231
T31 Phosphorylation HPRD   PhosphoSitePlus 20068231
S37 Phosphorylation HPRD   PhosphoSitePlus 20068231
K48 Methylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
Y72 Phosphorylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
S12 Y12 Biomuta DOID:363 / uterine cancer [ icgc ]
S12 F12 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y72 C72 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]