iPTMnet Report for Q9Y2M0 (FAN1)
Protein Information
UniProt AC / UniProt ID | Q9Y2M0 / FAN1_HUMAN |
Protein Name | Fanconi-associated nuclease 1 |
Gene Name | Name: FAN1 Synonyms:KIAA1018; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y2M0 |
PRO Name | Fanconi-associated nuclease 1 (human) |
Definition | A Fanconi-associated nuclease 1 that is encoded in the genome of human. |
Short Label | hFAN1 |
Category | organism-gene |
Q9Y2M0 (FAN1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
T110 | Phosphorylation | score1 | PhosphoSitePlus | |||
S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
S126 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 34330701 | ||
Y128 | Phosphorylation | score1 | PhosphoSitePlus | |||
S131 | Phosphorylation | score1 | PhosphoSitePlus | |||
K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
S146 | Phosphorylation | score1 | PhosphoSitePlus | |||
S154 | Phosphorylation | score1 | PhosphoSitePlus | |||
S160 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y163 | Phosphorylation | score1 | PhosphoSitePlus | |||
S169 | Phosphorylation | score1 | PhosphoSitePlus | |||
S180 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S197 | Phosphorylation | score1 | PhosphoSitePlus | |||
T254 | Phosphorylation | score1 | PhosphoSitePlus | |||
S258 | Phosphorylation | score1 | PhosphoSitePlus | |||
K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
S317 | Phosphorylation | score1 | PhosphoSitePlus | |||
K493 | Ubiquitination | score1 | PhosphoSitePlus | |||
K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
K516 | Ubiquitination | score1 | PhosphoSitePlus | |||
C538 | Methylation | score1 | IEDB | 31844290 | ||
K592 | Ubiquitination | score1 | PhosphoSitePlus | |||
K628 | Ubiquitination | score1 | PhosphoSitePlus | |||
K635 | Ubiquitination | score1 | PhosphoSitePlus | |||
S646 | Phosphorylation | score1 | PhosphoSitePlus | |||
S692 | Phosphorylation | score1 | PhosphoSitePlus | |||
K720 | Ubiquitination | score1 | PhosphoSitePlus | |||
K727 | Ubiquitination | score1 | PhosphoSitePlus | |||
K977 | Ubiquitination | score1 | PhosphoSitePlus | |||
K986 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y128 | H128 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
S160 | P160 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S160 | C160 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S692 | R692 | Biomuta | DOID:4362 / cervical cancer [ icgc ] |