iPTMnet Report for Q9Y2J4 (AMOTL2)
Protein Information
UniProt AC / UniProt ID | Q9Y2J4 / AMOL2_HUMAN |
Protein Name | Angiomotin-like protein 2 |
Gene Name | Name: AMOTL2 Synonyms:KIAA0989; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y2J4 |
PRO Name | angiomotin-like protein 2 (human) |
Definition | An angiomotin-like protein 2 that is encoded in the genome of human. |
Short Label | hAMOTL2 |
Category | organism-gene |
Q9Y2J4 (AMOTL2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T10 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y22 | Phosphorylation | score1 | PhosphoSitePlus | |||
T45 | Phosphorylation | score1 | PhosphoSitePlus | |||
S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y92 | Phosphorylation | score1 | PhosphoSitePlus | |||
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y107 | Phosphorylation | score3 | PhosphoSitePlus Signor | 21937427 | ||
Y107 | Phosphorylation | P11362 (FGFR1) | score3 | PhosphoSitePlus Signor | 21937427 | |
S157 | Phosphorylation | score1 | PhosphoSitePlus | |||
S159 | Phosphorylation | score2 | PhosphoSitePlus | 24225952 | ||
S159 | Phosphorylation | Q9NRM7 (LATS2) | score2 | PhosphoSitePlus | 24225952 | |
S166 | Phosphorylation | score1 | PhosphoSitePlus | |||
S176 | Phosphorylation | score1 | PhosphoSitePlus | |||
S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
R197 | Methylation | score1 | PhosphoSitePlus | |||
S236 | Phosphorylation | score1 | PhosphoSitePlus | |||
K347 | Ubiquitination | score1 | PhosphoSitePlus | |||
T375 | O-Glycosylation | score1 | GlyGen | 30379171, 29237092 | ||
K408 | Ubiquitination | score1 | PhosphoSitePlus | |||
K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
K436 | Ubiquitination | score1 | PhosphoSitePlus | |||
K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
K519 | Sumoylation | score1 | PhosphoSitePlus | |||
S537 | Phosphorylation | score1 | PhosphoSitePlus | |||
S540 | Phosphorylation | score1 | PhosphoSitePlus | |||
K568 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y573 | Phosphorylation | score1 | PhosphoSitePlus | |||
T596 | Phosphorylation | score1 | PhosphoSitePlus | |||
S602 | Phosphorylation | score1 | PhosphoSitePlus | |||
S606 | Phosphorylation | score1 | PhosphoSitePlus | |||
S608 | Phosphorylation | score1 | PhosphoSitePlus | |||
S609 | Phosphorylation | score1 | PhosphoSitePlus | |||
S610 | Phosphorylation | score1 | PhosphoSitePlus | |||
K630 | Ubiquitination | score1 | PhosphoSitePlus | |||
S661 | Phosphorylation | score1 | PhosphoSitePlus | |||
S667 | Phosphorylation | score1 | PhosphoSitePlus | |||
S753 | Phosphorylation | score1 | PhosphoSitePlus | |||
S759 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 25998128, 24275569 | ||
S759 | Phosphorylation | P42345 (MTOR) | score2 | PhosphoSitePlus | 25998128 | |
S762 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S54 | Phosphorylation | score0 | HPRD | 20068231 | ||
S183 | Phosphorylation | score0 | HPRD | 19651622 | ||
S236 | Phosphorylation | score0 | HPRD | 19691289 | ||
S534 | Phosphorylation | score0 | HPRD | 20068231 | ||
S540 | Phosphorylation | score0 | HPRD | 19664994, 19691289, 20068231 | ||
T597 | Phosphorylation | score0 | HPRD | 20068231 | ||
S606 | Phosphorylation | score0 | HPRD | 20068231 | ||
S661 | Phosphorylation | score0 | HPRD | 19691289 | ||
S760 | Phosphorylation | score0 | HPRD | 19007248, 19691289 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S157 | L157 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S176 | G176 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S236 | C236 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K422 | R422 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
S540 | F540 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S602 | Y602 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S602 | F602 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S606 | L606 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S667 | L667 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc, cosmic ] |