iPTMnet Report for Q9Y295 (DRG1)
Protein Information
UniProt AC / UniProt ID | Q9Y295 / DRG1_HUMAN |
Protein Name | Developmentally-regulated GTP-binding protein 1 |
Gene Name | Name: DRG1 Synonyms:NEDD3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y295 |
PRO Name | developmentally-regulated GTP-binding protein 1 (human) |
Definition | A developmentally-regulated GTP-binding protein 1 that is encoded in the genome of human. |
Short Label | hDRG1 |
Category | organism-gene |
Q9Y295 (DRG1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 22814378 | ||
K7 | Ubiquitination | score1 | PhosphoSitePlus | |||
K22 | Ubiquitination | score1 | PhosphoSitePlus | |||
K32 | Ubiquitination | score1 | PhosphoSitePlus | |||
K46 | Ubiquitination | score1 | PhosphoSitePlus | |||
K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y94 | Phosphorylation | score1 | PhosphoSitePlus | |||
T100 | Phosphorylation | score3 | neXtProt UniProt | 18184589 | ||
T100 | Phosphorylation | O75716 (STK16) | score2 | neXtProt | 18184589 | |
T101 | Phosphorylation | score2 | PhosphoSitePlus | 18184589 | ||
T101 | Phosphorylation | O75716 (STK16) | score2 | PhosphoSitePlus | 18184589 | |
K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
K159 | Ubiquitination | score1 | PhosphoSitePlus | |||
K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
K213 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y240 | Phosphorylation | score1 | PhosphoSitePlus | |||
C243 | Methylation | score1 | IEDB | 31844290 | ||
Y262 | Phosphorylation | score1 | PhosphoSitePlus | |||
C267 | Methylation | score1 | IEDB | 31844290 | ||
K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
T296 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y305 | Phosphorylation | score1 | PhosphoSitePlus | |||
T306 | Phosphorylation | score1 | PhosphoSitePlus | |||
S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y313 | Phosphorylation | score1 | PhosphoSitePlus | |||
K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
K331 | Ubiquitination | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
K352 | Ubiquitination | score1 | PhosphoSitePlus | |||
K366 | Ubiquitination | score1 | PhosphoSitePlus | |||
K367 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K159 | R159 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K213 | N213 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
Y240 | F240 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S307 | F307 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
K324 | M324 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K352 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] |