Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y295 / DRG1_HUMAN
Protein Name Developmentally-regulated GTP-binding protein 1
Gene Name Name: DRG1
Synonyms:NEDD3;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y295
DAG View
PRO Name developmentally-regulated GTP-binding protein 1 (human)
Definition A developmentally-regulated GTP-binding protein 1 that is encoded in the genome of human.
Short Label hDRG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y295 (DRG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
K7 Ubiquitination PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
T100 Phosphorylation O75716 (STK16) neXtProt   RLIMS-P   UniProt 18184589
T101 Phosphorylation O75716 (STK16) PhosphoSitePlus 18184589
K112 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
Y305 Phosphorylation PhosphoSitePlus
T306 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K367 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K159 R159 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K213 N213 Biomuta DOID:1612 / breast cancer [ tcga ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S307 F307 Biomuta DOID:4362 / cervical cancer [ icgc, tcga ]
K324 M324 Biomuta DOID:363 / uterine cancer [ tcga ]