iPTMnet Report for Q9UQL6 (HDAC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UQL6 / HDAC5_HUMAN
Protein Name Histone deacetylase 5
Gene Name Name: HDAC5
Synonyms:KIAA0600;
Organism Homo sapiens (Human)

PRO ID PR:Q9UQL6
DAG View
PRO Name histone deacetylase 5 (human)
Definition A histone deacetylase 5 that is encoded in the genome of human.
Short Label hHDAC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UQL6 (HDAC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
K35 Sumoylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
T70 Phosphorylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
S259 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 24207022, 17468767, 11081517, ...21146494, 18332134, 21892142, 16584705, 16980613, 18184930, 26061431, 12058061, 11114197, 24841198, 29339432
S259 Phosphorylation O43318 (MAP3K7) PhosphoSitePlus 16980613
S259 Phosphorylation P54646 (PRKAA2) PhosphoSitePlus 18184930
S259 Phosphorylation P57059 (SIK1) neXtProt 17468767
S259 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus   Signor 21146494, 18332134
S259 Phosphorylation Q13131 (PRKAA1) neXtProt   PhosphoSitePlus   Signor 18184930, 21892142
S259 Phosphorylation Q13555 (CAMK2G) Signor 11114197
S259 Phosphorylation Q14012 (CAMK1) neXtProt   PhosphoSitePlus   Signor 11114197, 11081517
S259 Phosphorylation Q15139 (PRKD1) PhosphoSitePlus 18332134
S259 Phosphorylation Q16566 (CAMK4) PhosphoSitePlus   Signor 11114197, 11081517, 12058061
S259 Phosphorylation Q7KZI7 (MARK2) PhosphoSitePlus 16980613
S259 Phosphorylation Q9UQM7 (CAMK2A) PhosphoSitePlus 24207022
S278 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 22865920, 21081666
S278 Phosphorylation Q96GD4 (AURKB) neXtProt   PhosphoSitePlus   Signor 22865920
S279 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor 23161540, 21081666, 27759007, ...20716686, 22865920, 15546868, 22243750
S279 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   Signor 20716686, 23161540, 22865920
S279 Phosphorylation Q00535 (CDK5) PhosphoSitePlus 22243750
S279 Phosphorylation Q9Y463 (DYRK1B) neXtProt 15546868
T288 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
T292 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 20188095
T292 Phosphorylation Q16512 (PKN1) neXtProt   PhosphoSitePlus 20188095
S368 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
T496 Phosphorylation PhosphoSitePlus
S498 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 24207022, 17468767, 11081517, ...21146494, 12058061, 22360269, 16584705, 21892142, 21998325, 18184930, 26061431, 22865920, 11114197, 18292392, 27667720, 18332134, 29339432
S498 Phosphorylation O94806 (PRKD3) neXtProt   PhosphoSitePlus 16584705
S498 Phosphorylation P54646 (PRKAA2) PhosphoSitePlus 18184930
S498 Phosphorylation P57059 (SIK1) neXtProt 17468767
S498 Phosphorylation Q05655 (PRKCD) Signor 18332134
S498 Phosphorylation Q13131 (PRKAA1) neXtProt   PhosphoSitePlus   Signor 18184930, 21892142
S498 Phosphorylation Q13555 (CAMK2G) Signor 11114197
S498 Phosphorylation Q13557 (CAMK2D) neXtProt 21998325, 22360269
S498 Phosphorylation Q14012 (CAMK1) neXtProt   PhosphoSitePlus   Signor 11114197, 11081517
S498 Phosphorylation Q15139 (PRKD1) neXtProt   PhosphoSitePlus   Signor 16584705, 21146494, 22865920, ...18332134
S498 Phosphorylation Q16566 (CAMK4) PhosphoSitePlus   Signor 11114197, 11081517, 12058061
S498 Phosphorylation Q9BZL6 (PRKD2) neXtProt   PhosphoSitePlus 16584705
S498 Phosphorylation Q9UQM7 (CAMK2A) PhosphoSitePlus 24207022
S504 Phosphorylation PhosphoSitePlus
K533 Acetylation PhosphoSitePlus   UniProt 19608861
K533 Sumoylation PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
T546 Phosphorylation PhosphoSitePlus
T547 Phosphorylation PhosphoSitePlus
K605 Sumoylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 24920159, 23186163
Y642 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus   UniProt 23186163
S671 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus   RLIMS-P 24920159, 21081666
Y776 Phosphorylation PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
S799 Phosphorylation PhosphoSitePlus
S1071 Phosphorylation PhosphoSitePlus
S1108 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 24920159, 23186163, 21081666
Site PTM Type PTM Enzyme Score Source PMID
S259 Phosphorylation HPRD   PRO 11114197, 11081517, 15367659, ...11509672
S259 Phosphorylation PR:Q14012 (hCAMK1) PRO 11114197, 11509672
S259 Phosphorylation Q14012 (CAMK1) HPRD 11114197, 11081517, 15367659
S259 Phosphorylation Q15139 (PRKD1) HPRD 11114197, 11081517, 15367659
S498 Phosphorylation HPRD   PRO 11114197, 11081517, 15367659, ...11509672
S498 Phosphorylation PR:Q14012 (hCAMK1) PRO 11114197, 11509672
S498 Phosphorylation Q14012 (CAMK1) HPRD 11114197, 11081517, 15367659
S498 Phosphorylation Q15139 (PRKD1) HPRD 11114197, 11081517, 15367659
Site PTM Type PTM Enzyme Score Source PMID
S260 Phosphorylation HPRD 11114197, 11081517, 15367659
S260 Phosphorylation Q14012 (CAMK1) HPRD 11114197, 11081517, 15367659
S260 Phosphorylation Q15139 (PRKD1) HPRD 11114197, 11081517, 15367659
S499 Phosphorylation HPRD 11114197, 11081517, 15367659
S499 Phosphorylation Q14012 (CAMK1) HPRD 11114197, 11081517, 15367659
S499 Phosphorylation Q15139 (PRKD1) HPRD 11114197, 11081517, 15367659


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000029006 (hHDAC5/iso:1/Phos:1) pS259,pS498 PR:Q14012 (hCAMK1) PRO 11114197, 11509672


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000029006 (hHDAC5/iso:1/Phos:1) Interaction PRO 11114197