iPTMnet Report for Q9UPY5 (SLC7A11)
Protein Information
UniProt AC / UniProt ID | Q9UPY5 / XCT_HUMAN |
Protein Name | Cystine/glutamate transporter |
Gene Name | Name: SLC7A11 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UPY5 |
PRO Name | cystine/glutamate transporter (human) |
Definition | A cystine/glutamate transporter that is encoded in the genome of human. |
Short Label | hSLC7A11 |
Category | organism-gene |
Q9UPY5 (SLC7A11) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K4 | Ubiquitination | score1 | PhosphoSitePlus | |||
S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
T9 | Phosphorylation | score1 | PhosphoSitePlus | |||
S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
K12 | Sumoylation | score1 | PhosphoSitePlus | |||
K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y15 | Phosphorylation | score1 | PhosphoSitePlus | |||
S26 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 18691976, 23186163, 17081983, ... | ||
K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
K37 | Ubiquitination | score1 | PhosphoSitePlus | |||
S51 | Phosphorylation | score1 | PhosphoSitePlus | |||
K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
S481 | Phosphorylation | score1 | PhosphoSitePlus | |||
K483 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S8 | F8 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K30 | N30 | Biomuta | DOID:363 / uterine cancer [ icgc ] |