Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9UPY5 / XCT_HUMAN
Protein Name Cystine/glutamate transporter
Gene Name Name: SLC7A11
Organism Homo sapiens (Human)

DAG View
PRO Name cystine/glutamate transporter (human)
Definition A cystine/glutamate transporter that is encoded in the genome of human.
Short Label hSLC7A11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9UPY5 (SLC7A11) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
T9 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
K12 Sumoylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
Y15 Phosphorylation PhosphoSitePlus
S26 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 23186163, 17081983, ...28648777, 19651622, 19369195
K30 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 F8 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K30 N30 Biomuta DOID:363 / uterine cancer [ tcga ]