iPTMnet Report for Q9ULC6 (PADI1)
Protein Information
| UniProt AC / UniProt ID | Q9ULC6 / PADI1_HUMAN |
| Protein Name | Protein-arginine deiminase type-1 |
| Gene Name | Name: PADI1 Synonyms:PAD1,PDI1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9ULC6 |
| PRO Name | protein-arginine deiminase type-1 (human) |
| Definition | A protein-arginine deiminase type-1 that is encoded in the genome of human. |
| Short Label | hPADI1 |
| Category | organism-gene |
Q9ULC6 (PADI1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K226 | Acetylation | score1 | PhosphoSitePlus | |||
| S326 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y327 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S439 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
| S494 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y595 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y602 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S45 | R45 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S45 | N45 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S45 | C45 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T72 | N72 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| T72 | I72 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S132 | R132 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S208 | F208 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View