Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKU0 / ACSL6_HUMAN
Protein Name Long-chain-fatty-acid--CoA ligase 6
Gene Name Name: ACSL6
Synonyms:ACS2,FACL6,KIAA0837,LACS5;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKU0
DAG View
PRO Name long-chain-fatty-acid--CoA ligase 6 (human)
Definition A long-chain-fatty-acid--CoA ligase 6 that is encoded in the genome of human.
Short Label hACSL6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKU0 (ACSL6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K143 Acetylation PhosphoSitePlus
T192 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
T549 Phosphorylation PhosphoSitePlus
K551 Ubiquitination PhosphoSitePlus
Y621 Phosphorylation PhosphoSitePlus
K643 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T311 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K143 I143 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S196 I196 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T197 I197 Biomuta DOID:4159 / skin cancer [ cosmic ]
K551 N551 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ icgc ]