iPTMnet Report for Q9UKU0 (ACSL6)
Protein Information
UniProt AC / UniProt ID | Q9UKU0 / ACSL6_HUMAN |
Protein Name | Long-chain-fatty-acid--CoA ligase 6 |
Gene Name | Name: ACSL6 Synonyms:ACS2,FACL6,KIAA0837,LACS5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UKU0 |
PRO Name | long-chain-fatty-acid--CoA ligase 6 (human) |
Definition | A long-chain-fatty-acid--CoA ligase 6 that is encoded in the genome of human. |
Short Label | hACSL6 |
Category | organism-gene |
Q9UKU0 (ACSL6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K143 | Acetylation | score1 | PhosphoSitePlus | |||
T192 | Phosphorylation | score1 | PhosphoSitePlus | |||
S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
T197 | Phosphorylation | score1 | PhosphoSitePlus | |||
K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
S379 | Phosphorylation | score1 | PhosphoSitePlus | |||
K395 | Ubiquitination | score1 | PhosphoSitePlus | |||
T549 | Phosphorylation | score1 | PhosphoSitePlus | |||
K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y621 | Phosphorylation | score1 | PhosphoSitePlus | |||
K643 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T311 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K143 | I143 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S196 | I196 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T197 | I197 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K551 | N551 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ icgc ] |