iPTMnet Report for Q9UKM7 (MAN1B1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKM7 / MA1B1_HUMAN
Protein Name Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Gene Name Name: MAN1B1
ORFNames:UNQ747/PRO1477;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKM7
DAG View
PRO Name endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (human)
Definition An endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase that is encoded in the genome of human.
Short Label hMAN1B1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKM7 (MAN1B1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T21 Phosphorylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
T144 O-Glycosylation GlyGen 25813380
K156 Ubiquitination PhosphoSitePlus
S174 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T186 O-Glycosylation GlyGen 25813380
T204 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T219 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S223 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T230 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380, ...35132862
T239 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
T242 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
Y248 O-Glycosylation GlyGen 25813380
K275 Ubiquitination PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
K354 Acetylation PhosphoSitePlus
S370 O-Glycosylation GlyGen 25813380
K371 Ubiquitination PhosphoSitePlus
T381 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K434 Ubiquitination PhosphoSitePlus
Y487 Phosphorylation PhosphoSitePlus
T508 O-Glycosylation PhosphoSitePlus
T565 Phosphorylation PhosphoSitePlus
Y577 Phosphorylation PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus
T697 O-Glycosylation GlyGen 25813380


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T219 I219 Biomuta [ cosmic ]
S370 F370 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T565 K565 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]