Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKM7 / MA1B1_HUMAN
Protein Name Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Gene Name Name: MAN1B1
ORFNames:UNQ747/PRO1477;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKM7
DAG View
PRO Name endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (human)
Definition An endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase that is encoded in the genome of human.
Short Label hMAN1B1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKM7 (MAN1B1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T21 Phosphorylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
S174 O-Glycosylation PhosphoSitePlus
T204 O-Glycosylation PhosphoSitePlus
T219 O-Glycosylation PhosphoSitePlus
S223 O-Glycosylation PhosphoSitePlus
T230 O-Glycosylation PhosphoSitePlus
T239 O-Glycosylation PhosphoSitePlus
T242 O-Glycosylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
K354 Acetylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
T381 O-Glycosylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
Y487 Phosphorylation PhosphoSitePlus
T508 O-Glycosylation PhosphoSitePlus
T565 Phosphorylation PhosphoSitePlus
Y577 Phosphorylation PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T21 R21 Biomuta DOID:363 / uterine cancer [ tcga ]
T565 K565 Biomuta DOID:3070 / malignant glioma [ tcga ]
K588 N588 Biomuta DOID:1790 / malignant mesothelioma [ tcga ]