iPTMnet Report for Q9UIK4 (DAPK2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UIK4 / DAPK2_HUMAN
Protein Name Death-associated protein kinase 2
Gene Name Name: DAPK2
Organism Homo sapiens (Human)

PRO ID PR:Q9UIK4
DAG View
PRO Name death-associated protein kinase 2 (human)
Definition A death-associated protein kinase 2 that is encoded in the genome of human.
Short Label hDAPK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UIK4 (DAPK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
Y49 Phosphorylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
S299 Phosphorylation Q13976 (PRKG1) neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 22580283, 23186163
S318 Phosphorylation Q9UIK4 (DAPK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 11230133, 34413451
S320 Phosphorylation PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S349 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
S367 Phosphorylation Q13976 (PRKG1) neXtProt   PhosphoSitePlus   RLIMS-P 22580283
S368 Phosphorylation Q13976 (PRKG1) neXtProt   PhosphoSitePlus   RLIMS-P 22580283
T369 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 26047703, 34413451
Site PTM Type PTM Enzyme Score Source PMID
S299 Phosphorylation HPRD 20166139
S318 Phosphorylation Q9UIK4 (DAPK2) HPRD 11230133
S349 Phosphorylation HPRD 18669648, 17081983


Q9UIK4 (DAPK2) as PTM Enzyme



Substrate Site Score Source PMID
Q8N122 (RPTOR) S721 RLIMS-P+ 25361081
Q9UIK4 (DAPK2) S318 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 11230133


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y49 H49 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S368 R368 Biomuta DOID:10534 / stomach cancer [ cosmic ]