iPTMnet Report for Q9UGC7 (MTRF1L)
Protein Information
UniProt AC / UniProt ID | Q9UGC7 / RF1ML_HUMAN |
Protein Name | Peptide chain release factor 1-like, mitochondrial precursor |
Gene Name | Name: MTRF1L Synonyms:MTRF1A; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UGC7 |
PRO Name | peptide chain release factor 1-like, mitochondrial (human) |
Definition | A peptide chain release factor 1-like, mitochondrial that is encoded in the genome of human. |
Short Label | hMTRF1L |
Category | organism-gene |
Q9UGC7 (MTRF1L) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K74 | Ubiquitination | score1 | PhosphoSitePlus | |||
K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
T218 | Phosphorylation | score1 | PhosphoSitePlus | |||
T228 | Phosphorylation | score1 | PhosphoSitePlus | |||
R245 | Methylation | score1 | PhosphoSitePlus | |||
Q252 | Methylation | score3 | UniProt | 35260756, 18541145 | ||
K379 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K105 | Q105 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
T228 | A228 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
R245 | Q245 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] |