iPTMnet Report for Q9UGC7 (MTRF1L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UGC7 / RF1ML_HUMAN
Protein Name Peptide chain release factor 1-like, mitochondrial precursor
Gene Name Name: MTRF1L
Synonyms:MTRF1A;
Organism Homo sapiens (Human)

PRO ID PR:Q9UGC7
DAG View
PRO Name peptide chain release factor 1-like, mitochondrial (human)
Definition A peptide chain release factor 1-like, mitochondrial that is encoded in the genome of human.
Short Label hMTRF1L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UGC7 (MTRF1L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K74 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
R245 Methylation PhosphoSitePlus
Q252 Methylation UniProt 35260756, 18541145
K379 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T218 Phosphorylation HPRD 17287340
T228 Phosphorylation HPRD 17287340


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K105 Q105 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T228 A228 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R245 Q245 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]