iPTMnet Report for Q9UEW8 (STK39)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UEW8 / STK39_HUMAN
Protein Name STE20/SPS1-related proline-alanine-rich protein kinase
Gene Name Name: STK39
Synonyms:PASK;
Organism Homo sapiens (Human)

PRO ID PR:Q9UEW8
DAG View
PRO Name STE20/SPS1-related proline-alanine-rich protein kinase (human)
Definition A STE20/SPS1-related proline-alanine-rich protein kinase that is encoded in the genome of human.
Short Label hSTK39
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UEW8 (STK39) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y63 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
C116 Methylation IEDB 31844290
K160 Ubiquitination PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
T231 Phosphorylation Q9UEW8 (STK39) , Q96J92 (WNK4) , Q9H4A3 (WNK1) neXtProt   PhosphoSitePlus   Signor   UniProt 16832045, 20463172, 34289367, ...21321328, 16083423, 17190791, 19633012, 16382158, 16263722, 16950202
T235 Phosphorylation Q9UEW8 (STK39) neXtProt   PhosphoSitePlus 16382158, 16950202
Y273 Phosphorylation PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
Y306 Phosphorylation PhosphoSitePlus
S309 Phosphorylation Q04759 (PRKCQ) neXtProt   PhosphoSitePlus   UniProt 14988727
K312 Acetylation PhosphoSitePlus
K312 Methylation PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K320 Methylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
S323 Phosphorylation Q04759 (PRKCQ) PhosphoSitePlus 14988727
K324 Ubiquitination PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K349 Acetylation PhosphoSitePlus   UniProt 19608861
K349 Ubiquitination PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
T354 Phosphorylation Q9Y3S1 (WNK2) PhosphoSitePlus   UniProt 23186163, 21733846
S370 Phosphorylation PhosphoSitePlus   UniProt 18088087
S371 Phosphorylation Q9H4A3 (WNK1) , Q9Y3S1 (WNK2) , Q96J92 (WNK4) neXtProt   PhosphoSitePlus   Signor   UniProt 20463172, 18088087, 16083423, ...16263722, 19633012, 17190791, 18270262, 21733846
S385 Phosphorylation PhosphoSitePlus   UniProt 21406692, 18088087, 23186163, ...17487921, 19690332, 20068231
S401 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
Y444 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
R469 Methylation PhosphoSitePlus
K512 Acetylation PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K515 Ubiquitination PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S309 Phosphorylation Q04759 (PRKCQ) HPRD 10980603
S323 Phosphorylation Q04759 (PRKCQ) HPRD 10980603
S370 Phosphorylation HPRD 19651622, 18088087, 17081983
S371 Phosphorylation HPRD 19651622, 18088087
S385 Phosphorylation HPRD 19413330, 17322306, 18088087, ...18452278, 19651622, 18510355, 19415658, 20068231


Q9UEW8 (STK39) as PTM Enzyme



Substrate Site Score Source PMID
P55011 (SLC12A2) T203 neXtProt   PhosphoSitePlus 16669787, 16950202, 16382158, ...21423148, 20091762
P55011 (SLC12A2) T207 neXtProt   PhosphoSitePlus 16669787, 16950202, 16382158, ...21423148, 20091762
P55011 (SLC12A2) T212 neXtProt   PhosphoSitePlus 16669787, 16950202, 16382158, ...21423148, 20091762
P55017 (SLC12A3) T46 neXtProt   PhosphoSitePlus 18270262, 21423148, 20091762
P55017 (SLC12A3) T55 neXtProt   PhosphoSitePlus 18270262, 21423148, 20091762
P55017 (SLC12A3) T60 neXtProt   PhosphoSitePlus 18270262, 21423148, 20091762
P55017 (SLC12A3) S91 neXtProt 18270262, 21423148, 20091762
Q13621 (SLC12A1) S91 Signor 21321328
Q13621 (SLC12A1) T95 neXtProt   PhosphoSitePlus   Signor 21423148, 21321328, 20091762
Q13621 (SLC12A1) T100 neXtProt   PhosphoSitePlus   Signor 21423148, 21321328, 20091762
Q13621 (SLC12A1) T105 neXtProt   PhosphoSitePlus   Signor 21423148, 21321328, 20091762
Q9H2X9 (SLC12A5) T6 PhosphoSitePlus 24393035
Q9H2X9 (SLC12A5) T1032 PhosphoSitePlus 24393035
Q9UEW8 (STK39) T231 neXtProt 16382158, 16950202
Q9UEW8 (STK39) T235 neXtProt 16382158, 16950202
Q9UHW9 (SLC12A6) S96 PhosphoSitePlus 24043619, 24393035
Q9UHW9 (SLC12A6) T160 PhosphoSitePlus 24393035
Q9UHW9 (SLC12A6) T1048 PhosphoSitePlus 24393035
Q9UP95 (SLC12A4) T5 PhosphoSitePlus 24393035
Q9UP95 (SLC12A4) T983 PhosphoSitePlus 24393035
Q9Y666 (SLC12A7) T973 PhosphoSitePlus 24393035
Q9Y666 (SLC12A7) T980 PhosphoSitePlus 24393035
Q9Y6R1 (SLC4A4) T49 neXtProt 21317537, 23431199
Q9Y6R1 (SLC4A4) S65 neXtProt   PhosphoSitePlus 21317537, 23431199