Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9UET6 / TRM7_HUMAN
Protein Name Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
Gene Name Name: FTSJ1
Organism Homo sapiens (Human)

DAG View
PRO Name putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (human)
Definition A ribosomal RNA methyltransferase 1 that is encoded in the genome of human.
Short Label hFTSJ1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9UET6 (FTSJ1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y12 Phosphorylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
T164 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
K261 Sumoylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
Y262 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T263 Phosphorylation PhosphoSitePlus
S271 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y274 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
K281 Methylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
S328 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Site PTM Type PTM Enzyme Score Source PMID
Y262 Phosphorylation HPRD 18669648
S271 Phosphorylation HPRD 19413330, 18669648
T302 Phosphorylation HPRD 20068231
S326 Phosphorylation HPRD 18691976
S328 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S217 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation HPRD 18669648
S269 Phosphorylation HPRD 19413330, 18669648
T300 Phosphorylation HPRD 20068231
S324 Phosphorylation HPRD 18691976
S326 Phosphorylation HPRD 18669648, 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T164 M164 Biomuta DOID:3070 / malignant glioma [ cosmic ]
T164 A164 Biomuta DOID:1324 / lung cancer [ tcga ]
Y262 C262 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc ]
S271 L271 Biomuta DOID:363 / uterine cancer [ tcga ]
T302 K302 Biomuta DOID:3571 / liver cancer [ icgc ]