iPTMnet Report for Q9UET6 (FTSJ1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UET6 / TRM7_HUMAN
Protein Name tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
Gene Name Name: FTSJ1
ORFNames:JM23;
Organism Homo sapiens (Human)

PRO ID PR:Q9UET6
DAG View
PRO Name putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (human)
Definition A ribosomal RNA methyltransferase 1 that is encoded in the genome of human.
Short Label hFTSJ1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UET6 (FTSJ1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y12 Phosphorylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
T164 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
K261 Sumoylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
Y262 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T263 Phosphorylation PhosphoSitePlus
S271 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y274 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
K281 Methylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
C295 Methylation IEDB 31844290
S298 O-Glycosylation GlyGen 35254053
T302 Phosphorylation PhosphoSitePlus
S328 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Site PTM Type PTM Enzyme Score Source PMID
Y262 Phosphorylation HPRD 18669648
S271 Phosphorylation HPRD 19413330, 18669648
T302 Phosphorylation HPRD 20068231
S326 Phosphorylation HPRD 18691976
S328 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S217 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation HPRD 18669648
S269 Phosphorylation HPRD 19413330, 18669648
T300 Phosphorylation HPRD 20068231
S324 Phosphorylation HPRD 18691976
S326 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T164 A164 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T164 M164 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y260 C260 Biomuta DOID:1319 / brain cancer [ cosmic ]
K261 M261 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y262 C262 Biomuta DOID:1319 / brain cancer [ cosmic ]
S269 L269 Biomuta DOID:363 / uterine cancer [ icgc ]
S271 L271 Biomuta DOID:363 / uterine cancer [ icgc ]
S324 C324 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S326 C326 Biomuta DOID:4606 / bile duct cancer [ cosmic ]