iPTMnet Report for Q9R1E0 (Foxo1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9R1E0 / FOXO1_MOUSE
Protein Name Forkhead box protein O1
Gene Name Name: Foxo1
Synonyms:Fkhr,Foxo1a;
Organism Mus musculus (Mouse)

PRO ID PR:Q9R1E0
DAG View
PRO Name forkhead box protein O1 (mouse)
Definition A forkhead box protein O1 that is encoded in the genome of mouse.
Short Label mFOXO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9R1E0 (Foxo1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T24 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 10377430, 28267764, 30174230, ...10347145, 33138208, 19965929, 20519497, 24466179, 11570877
T24 Phosphorylation P31750 (Akt1) PhosphoSitePlus 11570877, 10377430
T24 Phosphorylation Q9WVC6 (Sgk1) Signor 19965929
S209 Phosphorylation PhosphoSitePlus   RLIMS-P 33229443
S232 Phosphorylation PhosphoSitePlus
K242 Acetylation PhosphoSitePlus   UniProt 16076959, 17090532, 15220471
K245 Acetylation PhosphoSitePlus   UniProt 16076959, 17090532, 15220471
S246 Phosphorylation PhosphoSitePlus 18356527, 17113751
S246 Phosphorylation P11440 (Cdk1) PhosphoSitePlus 18356527
S246 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
R248 Methylation UniProt 18951090
R250 Methylation UniProt 18951090
S253 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 10377430, 11375271, 18388859, ...23705021, 24116102, 28270438, 22532369, 10347145, 19965929, 30014903, 20519497, 28644433, 16076959, 27827363
S253 Phosphorylation P31750 (Akt1) PhosphoSitePlus 10377430, 11375271
K259 Acetylation PhosphoSitePlus
K262 Acetylation PhosphoSitePlus   UniProt 16076959, 17090532, 15220471
K271 Acetylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus   RLIMS-P 33408127, 34208360
S284 Phosphorylation PhosphoSitePlus   UniProt 21183079, 17113751
S284 Phosphorylation P47811 (Mapk14) PhosphoSitePlus 17113751
S284 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
S295 Phosphorylation PhosphoSitePlus   UniProt 21183079, 17113751
S295 Phosphorylation P47811 (Mapk14) PhosphoSitePlus 17113751
S295 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
S300 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus   UniProt 11570877, 10347145
S316 Phosphorylation P31750 (Akt1) PhosphoSitePlus 11570877
S319 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 30002415, 19965929, 35966593
T320 Phosphorylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus   UniProt 21183079, 17113751
S326 Phosphorylation P47811 (Mapk14) PhosphoSitePlus 17113751
S326 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
T330 Phosphorylation PhosphoSitePlus   UniProt 21183079
S380 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus 17113751
S413 Phosphorylation P47811 (Mapk14) PhosphoSitePlus 17113751
S413 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
S415 Phosphorylation PhosphoSitePlus 17113751
S415 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
S429 Phosphorylation PhosphoSitePlus 17113751
S429 Phosphorylation P47811 (Mapk14) PhosphoSitePlus 17113751
S429 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
T464 Phosphorylation phospho.ELM   PhosphoSitePlus 17242355
S465 Phosphorylation phospho.ELM   PhosphoSitePlus 17242355
S467 Phosphorylation PhosphoSitePlus 17113751
S467 Phosphorylation P47811 (Mapk14) PhosphoSitePlus 17113751
S467 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
S475 Phosphorylation PhosphoSitePlus 17113751
S475 Phosphorylation P47811 (Mapk14) PhosphoSitePlus 17113751
S475 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
S499 Phosphorylation PhosphoSitePlus
T553 Phosphorylation PhosphoSitePlus
T557 Phosphorylation PhosphoSitePlus 17113751
T557 Phosphorylation P47811 (Mapk14) PhosphoSitePlus 17113751
T557 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
T644 O-Glycosylation GlyGen 32782141, 34678516
T645 O-Glycosylation GlyGen 32782141, 32848054
T646 O-Glycosylation GlyGen 34678516, 28528544, 32782141, ...24730386, 28052965, 25153642, 25142777, 32783937, 25944660


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P31750 (Akt1) S473 Q9R1E0 (Foxo1) unknown eFIP 29410630


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:O35426-2 (mXBP1/iso:2) Interaction PR:Q9R1E0 (mFOXO1) PRO 21317886