Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9R1E0 / FOXO1_MOUSE
Protein Name Forkhead box protein O1
Gene Name Name: Foxo1
Synonyms:Fkhr,Foxo1a;
Organism Mus musculus (Mouse)

PRO ID PR:Q9R1E0
DAG View
PRO Name forkhead box protein O1 (mouse)
Definition A forkhead box protein O1 that is encoded in the genome of mouse.
Short Label mFOXO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9R1E0 (Foxo1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T24 Phosphorylation P31750 (Akt1) , Q9WVC6 (Sgk1) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 10377430, 28267764, 30174230, ...10347145, 19965929, 20519497, 24466179, 11570877
S209 Phosphorylation PhosphoSitePlus   RLIMS-P 33229443
K242 Acetylation PhosphoSitePlus   UniProt 16076959, 17090532, 15220471
K245 Acetylation PhosphoSitePlus   UniProt 16076959, 17090532, 15220471
S246 Phosphorylation P63085 (Mapk1) , P11440 (Cdk1) PhosphoSitePlus 18356527, 17113751
R248 Methylation UniProt 18951090
R250 Methylation UniProt 18951090
S253 Phosphorylation P31750 (Akt1) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 10377430, 11375271, 18388859, ...24116102, 28270438, 22532369, 10347145, 19965929, 30014903, 20519497, 28644433, 16076959, 30951171
K262 Acetylation PhosphoSitePlus   UniProt 16076959, 17090532, 15220471
S273 Phosphorylation PhosphoSitePlus   RLIMS-P 33408127
S276 Phosphorylation RLIMS-P 30201683
S284 Phosphorylation P63085 (Mapk1) , P47811 (Mapk14) PhosphoSitePlus   UniProt 21183079, 17113751
S295 Phosphorylation P63085 (Mapk1) , P47811 (Mapk14) PhosphoSitePlus   UniProt 21183079, 17113751
S300 Phosphorylation PhosphoSitePlus
S316 Phosphorylation P31750 (Akt1) PhosphoSitePlus   UniProt 11570877, 10347145
S319 Phosphorylation PhosphoSitePlus   UniProt 19965929
T320 Phosphorylation PhosphoSitePlus
S326 Phosphorylation P63085 (Mapk1) , P47811 (Mapk14) PhosphoSitePlus   UniProt 21183079, 17113751
T330 Phosphorylation PhosphoSitePlus   UniProt 21183079
S380 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
S413 Phosphorylation P47811 (Mapk14) , P63085 (Mapk1) PhosphoSitePlus 17113751
S415 Phosphorylation P63085 (Mapk1) PhosphoSitePlus 17113751
S429 Phosphorylation P63085 (Mapk1) , P47811 (Mapk14) PhosphoSitePlus 17113751
T464 Phosphorylation phospho.ELM   PhosphoSitePlus 17242355
S465 Phosphorylation phospho.ELM   PhosphoSitePlus 17242355
S467 Phosphorylation P63085 (Mapk1) , P47811 (Mapk14) PhosphoSitePlus 17113751
S475 Phosphorylation P63085 (Mapk1) , P47811 (Mapk14) PhosphoSitePlus 17113751
S499 Phosphorylation PhosphoSitePlus
T553 Phosphorylation PhosphoSitePlus
T557 Phosphorylation P63085 (Mapk1) , P47811 (Mapk14) PhosphoSitePlus 17113751


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P31750 (Akt1) S473 Q9R1E0 (Foxo1) unknown eFIP 29410630


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:O35426-2 (mXBP1/iso:2) Interaction PR:Q9R1E0 (mFOXO1) PRO 21317886