iPTMnet Report for Q9P0U3 (SENP1)
Protein Information
UniProt AC / UniProt ID | Q9P0U3 / SENP1_HUMAN |
Protein Name | Sentrin-specific protease 1 |
Gene Name | Name: SENP1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9P0U3 |
PRO Name | sentrin-specific protease 1 (human) |
Definition | A sentrin-specific protease 1 that is encoded in the genome of human. |
Short Label | hSENP1 |
Category | organism-gene |
Q9P0U3 (SENP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S57 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T59 | Phosphorylation | score1 | PhosphoSitePlus | |||
S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
S80 | Phosphorylation | score1 | PhosphoSitePlus | |||
T102 | Phosphorylation | score1 | PhosphoSitePlus | |||
K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
S117 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K124 | Methylation | score1 | PhosphoSitePlus | |||
K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
S132 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
K136 | Methylation | score1 | PhosphoSitePlus | |||
K136 | Ubiquitination | score1 | PhosphoSitePlus | |||
S149 | Phosphorylation | score1 | PhosphoSitePlus | |||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
S157 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S159 | Phosphorylation | score1 | PhosphoSitePlus | |||
S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
S167 | Phosphorylation | score1 | PhosphoSitePlus | |||
S170 | Phosphorylation | score1 | PhosphoSitePlus | |||
S180 | Phosphorylation | score1 | PhosphoSitePlus | |||
K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
S226 | Phosphorylation | score1 | PhosphoSitePlus | |||
K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
K231 | Ubiquitination | score1 | PhosphoSitePlus | |||
S233 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y270 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 35186948 | ||
T328 | Phosphorylation | score1 | PhosphoSitePlus | |||
T330 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y349 | Phosphorylation | score1 | PhosphoSitePlus | |||
K364 | Acetylation | score1 | PhosphoSitePlus | |||
K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
S381 | Phosphorylation | score1 | PhosphoSitePlus | |||
K396 | Acetylation | score1 | PhosphoSitePlus | |||
K396 | Ubiquitination | score1 | PhosphoSitePlus | |||
T414 | Phosphorylation | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
K429 | Acetylation | score1 | PhosphoSitePlus | |||
K429 | Ubiquitination | score1 | PhosphoSitePlus | |||
K432 | Ubiquitination | score1 | PhosphoSitePlus | |||
K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
K510 | Ubiquitination | score1 | PhosphoSitePlus | |||
C560 | Methylation | score1 | IEDB | 31844290 | ||
K577 | Ubiquitination | score1 | PhosphoSitePlus | |||
K609 | Ubiquitination | score1 | PhosphoSitePlus | |||
K616 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S57 | F57 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T59 | A59 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T59 | I59 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S78 | L78 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S80 | R80 | Biomuta | DOID:10534 / stomach cancer [ icgc ] | |
S80 | G80 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S127 | N127 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S130 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S149 | Y149 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S180 | N180 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T328 | I328 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K364 | T364 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K432 | N432 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K609 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] |