iPTMnet Report for Q9NZC2 (TREM2)
Protein Information
| UniProt AC / UniProt ID | Q9NZC2 / TREM2_HUMAN |
| Protein Name | Triggering receptor expressed on myeloid cells 2 precursor |
| Gene Name | Name: TREM2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NZC2 |
| PRO Name | triggering receptor expressed on myeloid cells 2 (human) |
| Definition | A triggering receptor expressed on myeloid cells 2 that is encoded in the genome of human. |
| Short Label | hTREM2 |
| Category | organism-gene |
Q9NZC2 (TREM2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| N20 | N-Glycosylation | score3 | GlyGen UniProt | 29794134 | ||
| N79 | N-Glycosylation | score4 | GlyGen UniProt | 29794134, 27995897 | ||
| T88 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T92 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N20 | S20 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T88 | P88 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
DAG View