iPTMnet Report for Q9NZC2 (TREM2)
Protein Information
UniProt AC / UniProt ID | Q9NZC2 / TREM2_HUMAN |
Protein Name | Triggering receptor expressed on myeloid cells 2 precursor |
Gene Name | Name: TREM2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NZC2 |
PRO Name | triggering receptor expressed on myeloid cells 2 (human) |
Definition | A triggering receptor expressed on myeloid cells 2 that is encoded in the genome of human. |
Short Label | hTREM2 |
Category | organism-gene |
Q9NZC2 (TREM2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N20 | N-Glycosylation | score3 | GlyGen UniProt | 29794134 | ||
N79 | N-Glycosylation | score4 | GlyGen UniProt | 29794134, 27995897 | ||
T88 | Phosphorylation | score1 | PhosphoSitePlus | |||
T92 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N20 | S20 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T88 | P88 | Biomuta | DOID:363 / uterine cancer [ icgc ] |