iPTMnet Report for Q9NYP7 (ELOVL5)
Protein Information
| UniProt AC / UniProt ID | Q9NYP7 / ELOV5_HUMAN |
| Protein Name | Elongation of very long chain fatty acids protein 5 |
| Gene Name | Name: ELOVL5 Synonyms:ELOVL2;ORFNames:PRO0530; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NYP7 |
| PRO Name | elongation of very long chain fatty acids protein 5 (human) |
| Definition | An elongation of very long chain fatty acids protein 5 that is encoded in the genome of human. |
| Short Label | hELOVL5 |
| Category | organism-gene |
Q9NYP7 (ELOVL5) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 25944712 | ||
| K13 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C38 | Methylation | score1 | IEDB | 31844290 | ||
| K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C163 | Methylation | score1 | IEDB | 31844290 | ||
| K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S273 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T281 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S285 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S7 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T10 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T21 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S273 | Phosphorylation | score0 | HPRD | 17081983 | ||
| T281 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17081983, ... | ||
| S283 | Phosphorylation | score0 | HPRD | 18691976, 17081983, 20068231 | ||
| S285 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K13 | N13 | Biomuta | DOID:11054 / urinary bladder cancer [ icgc ] | |
| C163 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K267 | Q267 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S285 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S285 | L285 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View