iPTMnet Report for Q9NYP7 (ELOVL5)
Protein Information
UniProt AC / UniProt ID | Q9NYP7 / ELOV5_HUMAN |
Protein Name | Elongation of very long chain fatty acids protein 5 |
Gene Name | Name: ELOVL5 Synonyms:ELOVL2;ORFNames:PRO0530; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NYP7 |
PRO Name | elongation of very long chain fatty acids protein 5 (human) |
Definition | An elongation of very long chain fatty acids protein 5 that is encoded in the genome of human. |
Short Label | hELOVL5 |
Category | organism-gene |
Q9NYP7 (ELOVL5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 25944712 | ||
K13 | Ubiquitination | score1 | PhosphoSitePlus | |||
C38 | Methylation | score1 | IEDB | 31844290 | ||
K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
C163 | Methylation | score1 | IEDB | 31844290 | ||
K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
S273 | Phosphorylation | score1 | PhosphoSitePlus | |||
T281 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S283 | Phosphorylation | score1 | PhosphoSitePlus | |||
S285 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S7 | Phosphorylation | score0 | HPRD | 20068231 | ||
T10 | Phosphorylation | score0 | HPRD | 20068231 | ||
T21 | Phosphorylation | score0 | HPRD | 20068231 | ||
S273 | Phosphorylation | score0 | HPRD | 17081983 | ||
T281 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17081983, ... | ||
S283 | Phosphorylation | score0 | HPRD | 18691976, 17081983, 20068231 | ||
S285 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K13 | N13 | Biomuta | DOID:11054 / urinary bladder cancer [ icgc ] | |
C163 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K267 | Q267 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S285 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
S285 | L285 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |