iPTMnet Report for Q9NY27 (PPP4R2)
Protein Information
UniProt AC / UniProt ID | Q9NY27 / PP4R2_HUMAN |
Protein Name | Serine/threonine-protein phosphatase 4 regulatory subunit 2 |
Gene Name | Name: PPP4R2 ORFNames:SBBI57; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NY27 |
PRO Name | serine/threonine-protein phosphatase 4 regulatory subunit 2 (human) |
Definition | A serine/threonine-protein phosphatase 4 regulatory subunit 2 that is encoded in the genome of human. |
Short Label | hPPP4R2 |
Category | organism-gene |
Q9NY27 (PPP4R2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
K15 | Ubiquitination | score1 | PhosphoSitePlus | |||
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
K84 | Ubiquitination | score1 | PhosphoSitePlus | |||
K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
S138 | Phosphorylation | score1 | PhosphoSitePlus | |||
K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
S159 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 15302935, ... | ||
S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
T173 | Phosphorylation | score1 | PhosphoSitePlus | |||
S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
T190 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
S226 | Phosphorylation | score2 | IEDB phospho.ELM PhosphoSitePlus UniProt | 21406692, 17287340, 17081983, ... | ||
K229 | Ubiquitination | score1 | PhosphoSitePlus | |||
K231 | Ubiquitination | score1 | PhosphoSitePlus | |||
K246 | Acetylation | score1 | PhosphoSitePlus | |||
K246 | Ubiquitination | score1 | PhosphoSitePlus | |||
K252 | Acetylation | score1 | PhosphoSitePlus | |||
S311 | Phosphorylation | score1 | PhosphoSitePlus | |||
S361 | Phosphorylation | score1 | PhosphoSitePlus | |||
S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
S389 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S159 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
S161 | Phosphorylation | score0 | HPRD | 19664995 | ||
Y162 | Phosphorylation | score0 | HPRD | 20068231 | ||
S183 | Phosphorylation | score0 | HPRD | 20068231 | ||
S185 | Phosphorylation | score0 | HPRD | 20068231 | ||
T189 | Phosphorylation | score0 | HPRD | 20068231 | ||
T197 | Phosphorylation | score0 | HPRD | 20068231 | ||
S224 | Phosphorylation | score0 | HPRD | 20068231, 18452278 | ||
S226 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 18767875, ... | ||
T259 | Phosphorylation | score0 | HPRD | 20068231 | ||
T276 | Phosphorylation | score0 | HPRD | 20068231 | ||
S280 | Phosphorylation | score0 | HPRD | 20068231 | ||
S281 | Phosphorylation | score0 | HPRD | 20068231 | ||
S282 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K127 | Q127 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K127 | T127 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S159 | A159 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
S159 | * | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S183 | F183 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] | |
S223 | F223 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S224 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K229 | R229 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K229 | T229 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S282 | C282 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S282 | T282 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S311 | Y311 | Biomuta | DOID:363 / uterine cancer [ icgc ] |