iPTMnet Report for Q9NVS9 (PNPO)
Protein Information
UniProt AC / UniProt ID | Q9NVS9 / PNPO_HUMAN |
Protein Name | Pyridoxine-5'-phosphate oxidase |
Gene Name | Name: PNPO |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NVS9 |
PRO Name | pyridoxine-5'-phosphate oxidase (human) |
Definition | A pyridoxine-5'-phosphate oxidase that is encoded in the genome of human. |
Short Label | hPNPO |
Category | organism-gene |
Q9NVS9 (PNPO) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C3 | Methylation | score1 | IEDB | 31844290 | ||
S40 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
C156 | Methylation | score1 | IEDB | 31844290 | ||
C156 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
Y157 | Phosphorylation | score1 | PhosphoSitePlus | |||
S164 | Phosphorylation | score1 | PhosphoSitePlus | |||
S165 | Phosphorylation | score1 | PhosphoSitePlus | |||
S172 | Phosphorylation | score1 | PhosphoSitePlus | |||
R181 | Methylation | score1 | PhosphoSitePlus | |||
Y183 | Phosphorylation | score1 | PhosphoSitePlus | |||
K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y212 | Phosphorylation | score1 | PhosphoSitePlus | |||
T238 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S241 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S40 | N40 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y157 | H157 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
S164 | I164 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S165 | R165 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S241 | F241 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |