iPTMnet Report for Q9NVP1 (DDX18)
Protein Information
UniProt AC / UniProt ID | Q9NVP1 / DDX18_HUMAN |
Protein Name | ATP-dependent RNA helicase DDX18 |
Gene Name | Name: DDX18 Synonyms:cPERP-D; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NVP1 |
PRO Name | ATP-dependent RNA helicase DDX18 (human) |
Definition | An ATP-dependent RNA helicase DDX18 that is encoded in the genome of human. |
Short Label | hDDX18 |
Category | organism-gene |
Q9NVP1 (DDX18) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K7 | Acetylation | score1 | PhosphoSitePlus | |||
S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
T47 | Phosphorylation | score1 | PhosphoSitePlus | |||
S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
K57 | Acetylation | score1 | PhosphoSitePlus | |||
K59 | Acetylation | score1 | PhosphoSitePlus | |||
T68 | Phosphorylation | score1 | PhosphoSitePlus | |||
S74 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18077418 | ||
K82 | Acetylation | score1 | PhosphoSitePlus | |||
S86 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
T91 | Phosphorylation | score1 | PhosphoSitePlus | |||
S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
K126 | Acetylation | score1 | PhosphoSitePlus | |||
K135 | Sumoylation | score1 | PhosphoSitePlus | |||
S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
T225 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18491316 | ||
S227 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18491316 | ||
T230 | Phosphorylation | score1 | PhosphoSitePlus | |||
S258 | Phosphorylation | score1 | PhosphoSitePlus | |||
T260 | Phosphorylation | score1 | PhosphoSitePlus | |||
K297 | Ubiquitination | score1 | PhosphoSitePlus | |||
T308 | Phosphorylation | score1 | PhosphoSitePlus | |||
T319 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y324 | Phosphorylation | score1 | PhosphoSitePlus | |||
K348 | Ubiquitination | score1 | PhosphoSitePlus | |||
K352 | Acetylation | score1 | PhosphoSitePlus | |||
T356 | Phosphorylation | score1 | IEDB | 35494241 | ||
T360 | Phosphorylation | score1 | PhosphoSitePlus | |||
T368 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K370 | Ubiquitination | score1 | PhosphoSitePlus | |||
K380 | Sumoylation | score1 | PhosphoSitePlus | |||
K381 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y385 | Phosphorylation | score1 | PhosphoSitePlus | |||
S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y440 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y442 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y447 | Phosphorylation | score1 | PhosphoSitePlus | |||
K458 | Acetylation | score1 | PhosphoSitePlus | |||
K545 | Acetylation | score1 | PhosphoSitePlus | |||
K545 | Ubiquitination | score1 | PhosphoSitePlus | |||
S549 | Phosphorylation | score1 | PhosphoSitePlus | |||
K557 | Ubiquitination | score1 | PhosphoSitePlus | |||
K567 | Ubiquitination | score1 | PhosphoSitePlus | |||
K571 | Acetylation | score1 | PhosphoSitePlus | |||
K571 | Ubiquitination | score1 | PhosphoSitePlus | |||
K577 | Acetylation | score1 | PhosphoSitePlus | |||
K577 | Ubiquitination | score1 | PhosphoSitePlus | |||
K584 | Ubiquitination | score1 | PhosphoSitePlus | |||
R588 | Methylation | score1 | PhosphoSitePlus | |||
S627 | Phosphorylation | score1 | PhosphoSitePlus | |||
R635 | Methylation | score1 | PhosphoSitePlus | |||
Y643 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S36 | L36 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
K135 | E135 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T230 | A230 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T319 | I319 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K348 | N348 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T360 | A360 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T360 | N360 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S434 | F434 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S434 | Y434 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S437 | P437 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K545 | Q545 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K577 | M577 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
R588 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] |