iPTMnet Report for Q9NTX5 (ECHDC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NTX5 / ECHD1_HUMAN
Protein Name Ethylmalonyl-CoA decarboxylase
Gene Name Name: ECHDC1
Organism Homo sapiens (Human)

PRO ID PR:Q9NTX5
DAG View
PRO Name ethylmalonyl-CoA decarboxylase (human)
Definition An ethylmalonyl-CoA decarboxylase that is encoded in the genome of human.
Short Label hECHDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NTX5 (ECHDC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K9 Ubiquitination PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
S205 O-Glycosylation GlyGen 30379171, 28510447, 34229054
S205 Phosphorylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K217 Acetylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T104 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K9 E9 Biomuta DOID:363 / uterine cancer [ icgc ]
T175 I175 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K210 N210 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]