iPTMnet Report for Q9NTX5 (ECHDC1)
Protein Information
UniProt AC / UniProt ID | Q9NTX5 / ECHD1_HUMAN |
Protein Name | Ethylmalonyl-CoA decarboxylase |
Gene Name | Name: ECHDC1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NTX5 |
PRO Name | ethylmalonyl-CoA decarboxylase (human) |
Definition | An ethylmalonyl-CoA decarboxylase that is encoded in the genome of human. |
Short Label | hECHDC1 |
Category | organism-gene |
Q9NTX5 (ECHDC1) as Substrate
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
K13 | Ubiquitination | score1 | PhosphoSitePlus | |||
S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
K108 | Ubiquitination | score1 | PhosphoSitePlus | |||
T175 | Phosphorylation | score1 | PhosphoSitePlus | |||
K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
S205 | O-Glycosylation | score1 | GlyGen | 30379171, 28510447, 34229054 | ||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
K217 | Acetylation | score1 | PhosphoSitePlus | |||
K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
S235 | Phosphorylation | score1 | PhosphoSitePlus | |||
S236 | Phosphorylation | score1 | PhosphoSitePlus | |||
K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
T104 | Phosphorylation | score1 | PhosphoSitePlus | |||
K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
S131 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | T2 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K9 | E9 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T175 | I175 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K210 | N210 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |