iPTMnet Report for Q9NSD9 (FARSB)
Protein Information
UniProt AC / UniProt ID | Q9NSD9 / SYFB_HUMAN |
Protein Name | Phenylalanine--tRNA ligase beta subunit |
Gene Name | Name: FARSB Synonyms:FARSLB,FRSB;ORFNames:HSPC173; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NSD9 |
PRO Name | phenylalanine--tRNA ligase beta subunit (human) |
Definition | A eukaryotic-type phenylalanine--tRNA ligase beta subunit that is encoded in the genome of human. |
Short Label | hFARSB |
Category | organism-gene |
Q9NSD9 (FARSB) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S46 | Phosphorylation | score1 | PhosphoSitePlus | |||
K47 | Acetylation | score1 | PhosphoSitePlus | |||
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y63 | Phosphorylation | score1 | PhosphoSitePlus | |||
K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
R71 | Methylation | score1 | PhosphoSitePlus | |||
Y72 | Phosphorylation | score1 | PhosphoSitePlus | |||
K88 | Methylation | score1 | PhosphoSitePlus | |||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
K107 | Acetylation | score1 | PhosphoSitePlus | |||
K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y136 | Phosphorylation | score1 | PhosphoSitePlus | |||
S138 | Phosphorylation | score1 | PhosphoSitePlus | |||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
T161 | Phosphorylation | score1 | PhosphoSitePlus | |||
S168 | Phosphorylation | score1 | PhosphoSitePlus | |||
K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y192 | Phosphorylation | score1 | PhosphoSitePlus | |||
C195 | Methylation | score1 | IEDB | 31844290 | ||
K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
S226 | Phosphorylation | score1 | PhosphoSitePlus | |||
K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
K316 | Ubiquitination | score1 | PhosphoSitePlus | |||
K329 | Acetylation | score1 | PhosphoSitePlus | |||
K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
K395 | Ubiquitination | score1 | PhosphoSitePlus | |||
K435 | Ubiquitination | score1 | PhosphoSitePlus | |||
K443 | Ubiquitination | score1 | PhosphoSitePlus | |||
K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
K467 | Ubiquitination | score1 | PhosphoSitePlus | |||
K473 | Acetylation | score1 | PhosphoSitePlus | |||
K473 | Ubiquitination | score1 | PhosphoSitePlus | |||
S478 | Phosphorylation | score1 | PhosphoSitePlus | |||
K483 | Ubiquitination | score1 | PhosphoSitePlus | |||
K492 | Ubiquitination | score1 | PhosphoSitePlus | |||
C498 | Methylation | score1 | IEDB | 31844290 | ||
C498 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
R517 | Methylation | score1 | PhosphoSitePlus | |||
K530 | Ubiquitination | score1 | PhosphoSitePlus | |||
K536 | Ubiquitination | score1 | PhosphoSitePlus | |||
K560 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K47 | N47 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
R71 | T71 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
Y72 | H72 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S168 | L168 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
K182 | T182 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K395 | T395 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
K483 | Q483 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K536 | T536 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |