iPTMnet Report for Q9NSD9 (FARSB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NSD9 / SYFB_HUMAN
Protein Name Phenylalanine--tRNA ligase beta subunit
Gene Name Name: FARSB
Synonyms:FARSLB,FRSB;ORFNames:HSPC173;
Organism Homo sapiens (Human)

PRO ID PR:Q9NSD9
DAG View
PRO Name phenylalanine--tRNA ligase beta subunit (human)
Definition A eukaryotic-type phenylalanine--tRNA ligase beta subunit that is encoded in the genome of human.
Short Label hFARSB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NSD9 (FARSB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation PhosphoSitePlus
K47 Acetylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
Y63 Phosphorylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
R71 Methylation PhosphoSitePlus
Y72 Phosphorylation PhosphoSitePlus
K88 Methylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
Y136 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
Y192 Phosphorylation PhosphoSitePlus
C195 Methylation IEDB 31844290
K202 Ubiquitination PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K329 Acetylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
K473 Acetylation PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
C498 Methylation IEDB 31844290
C498 S-Nitrosylation dbSNO 26338901
R517 Methylation PhosphoSitePlus
K530 Ubiquitination PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
K560 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K47 N47 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R71 T71 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y72 H72 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S168 L168 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
K182 T182 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K395 T395 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K483 Q483 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K536 T536 Biomuta DOID:1612 / breast cancer [ cosmic ]