iPTMnet Report for Q9NR64 (KLHL1)
Protein Information
| UniProt AC / UniProt ID | Q9NR64 / KLHL1_HUMAN |
| Protein Name | Kelch-like protein 1 |
| Gene Name | Name: KLHL1 Synonyms:KIAA1490; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NR64 |
| PRO Name | kelch-like protein 1 (human) |
| Definition | A kelch-like protein 1 that is encoded in the genome of human. |
| Short Label | hKLHL1 |
| Category | organism-gene |
Q9NR64 (KLHL1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S77 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T444 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| K518 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T519 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T522 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K529 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T530 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T532 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y556 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T624 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S75 | T75 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S76 | C76 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S77 | T77 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T444 | I444 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T519 | K519 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T522 | S522 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T530 | I530 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y556 | D556 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View