iPTMnet Report for Q9NR64 (KLHL1)
Protein Information
UniProt AC / UniProt ID | Q9NR64 / KLHL1_HUMAN |
Protein Name | Kelch-like protein 1 |
Gene Name | Name: KLHL1 Synonyms:KIAA1490; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NR64 |
PRO Name | kelch-like protein 1 (human) |
Definition | A kelch-like protein 1 that is encoded in the genome of human. |
Short Label | hKLHL1 |
Category | organism-gene |
Q9NR64 (KLHL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
S77 | Phosphorylation | score1 | PhosphoSitePlus | |||
S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
T444 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
K518 | Ubiquitination | score1 | PhosphoSitePlus | |||
T519 | Phosphorylation | score1 | PhosphoSitePlus | |||
T522 | Phosphorylation | score1 | PhosphoSitePlus | |||
K529 | Ubiquitination | score1 | PhosphoSitePlus | |||
T530 | Phosphorylation | score1 | PhosphoSitePlus | |||
T532 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y556 | Phosphorylation | score1 | PhosphoSitePlus | |||
T624 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S75 | T75 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S76 | C76 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S77 | T77 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T444 | I444 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T519 | K519 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T522 | S522 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T530 | I530 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
Y556 | D556 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |