iPTMnet Report for Q9NR33 (POLE4)
Protein Information
| UniProt AC / UniProt ID | Q9NR33 / DPOE4_HUMAN |
| Protein Name | DNA polymerase epsilon subunit 4 |
| Gene Name | Name: POLE4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NR33 |
| PRO Name | DNA polymerase epsilon subunit 4 (human) |
| Definition | A DNA polymerase epsilon subunit 4 that is encoded in the genome of human. |
| Short Label | hPOLE4 |
| Category | organism-gene |
DAG ViewQ9NR33 (POLE4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22814378, 20068231 | ||
| T11 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19413330, 20068231 | ||
| S25 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332 | ||
| K51 | Sumoylation | score1 | PhosphoSitePlus | |||
| T57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C84 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
| C85 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
| K90 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S25 | L25 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
