iPTMnet Report for Q9NQX5 (NPDC1)
Protein Information
UniProt AC / UniProt ID | Q9NQX5 / NPDC1_HUMAN |
Protein Name | Neural proliferation differentiation and control protein 1 precursor |
Gene Name | Name: NPDC1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NQX5 |
PRO Name | neural proliferation differentiation and control protein 1 (human) |
Definition | A neural proliferation differentiation and control protein 1 that is encoded in the genome of human. |
Short Label | hNPDC1 |
Category | organism-gene |
Q9NQX5 (NPDC1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S114 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
T115 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
T115 | Phosphorylation | score1 | PhosphoSitePlus | |||
T130 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
S134 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
S161 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S164 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
K225 | Ubiquitination | score1 | PhosphoSitePlus | |||
S229 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 19007248, 20068231 | ||
S236 | Phosphorylation | score1 | PhosphoSitePlus | |||
S245 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y249 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y251 | Phosphorylation | score1 | PhosphoSitePlus | |||
S319 | Phosphorylation | score1 | PhosphoSitePlus | |||
S320 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S134 | L134 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S236 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S320 | L320 | Biomuta | DOID:1540 / parathyroid carcinoma [ cosmic ] |