iPTMnet Report for Q9NQX5 (NPDC1)
Protein Information
| UniProt AC / UniProt ID | Q9NQX5 / NPDC1_HUMAN |
| Protein Name | Neural proliferation differentiation and control protein 1 precursor |
| Gene Name | Name: NPDC1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NQX5 |
| PRO Name | neural proliferation differentiation and control protein 1 (human) |
| Definition | A neural proliferation differentiation and control protein 1 that is encoded in the genome of human. |
| Short Label | hNPDC1 |
| Category | organism-gene |
Q9NQX5 (NPDC1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S114 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| T115 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| T115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T130 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| S134 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| S161 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S164 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K225 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S229 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 19007248, 20068231 | ||
| S236 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S245 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y249 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y251 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S319 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S320 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S134 | L134 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S236 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S320 | L320 | Biomuta | DOID:1540 / parathyroid carcinoma [ cosmic ] |
DAG View