iPTMnet Report Q9NQV7 PRDM9

Protein Information

UniProt AC / UniProt ID	Q9NQV7 / PRDM9_HUMAN
Protein Name	Histone-lysine N-methyltransferase PRDM9
Gene Name	Name: PRDM9 Synonyms:PFM6;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9NQV7 DAG View
PRO Name	histone-lysine N-methyltransferase PRDM9 (human)
Definition	A histone-lysine N-methyltransferase PRDM9 that is encoded in the genome of human.
Short Label	hPRDM9
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9NQV7 (PRDM9) as Substrate

Q9NQV7

Expanded View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position T18 K21 K25 K29 T69 S128 S129 Y181 Y191 T545 T547 T575 T601 T603 T685 T687 T713 T715 T741 T743 S761 T769 T771 T797 T799 T825 T827 K844 T853 T855 T881 T883	PTM Type Select all Acetylation Phosphorylation Ubiquitination	Score Select all 1	Source Select all PhosphoSitePlus
T18	Phosphorylation	score1	PhosphoSitePlus
K21	Ubiquitination	score1	PhosphoSitePlus
K25	Ubiquitination	score1	PhosphoSitePlus
K29	Ubiquitination	score1	PhosphoSitePlus
T69	Phosphorylation	score1	PhosphoSitePlus
S128	Phosphorylation	score1	PhosphoSitePlus
S129	Phosphorylation	score1	PhosphoSitePlus
Y181	Phosphorylation	score1	PhosphoSitePlus
Y191	Phosphorylation	score1	PhosphoSitePlus
T545	Phosphorylation	score1	PhosphoSitePlus
T547	Phosphorylation	score1	PhosphoSitePlus
T575	Phosphorylation	score1	PhosphoSitePlus
T601	Phosphorylation	score1	PhosphoSitePlus
T603	Phosphorylation	score1	PhosphoSitePlus
T685	Phosphorylation	score1	PhosphoSitePlus
T687	Phosphorylation	score1	PhosphoSitePlus
T713	Phosphorylation	score1	PhosphoSitePlus
T715	Phosphorylation	score1	PhosphoSitePlus
T741	Phosphorylation	score1	PhosphoSitePlus
T743	Phosphorylation	score1	PhosphoSitePlus
S761	Phosphorylation	score1	PhosphoSitePlus
T769	Phosphorylation	score1	PhosphoSitePlus
T771	Phosphorylation	score1	PhosphoSitePlus
T797	Phosphorylation	score1	PhosphoSitePlus
T799	Phosphorylation	score1	PhosphoSitePlus
T825	Phosphorylation	score1	PhosphoSitePlus
T827	Phosphorylation	score1	PhosphoSitePlus
K844	Acetylation	score1	PhosphoSitePlus
T853	Phosphorylation	score1	PhosphoSitePlus
T855	Phosphorylation	score1	PhosphoSitePlus
T881	Phosphorylation	score1	PhosphoSitePlus
T883	Phosphorylation	score1	PhosphoSitePlus

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine By position T18 K21 K29 S128 S129 T545 T601 T603 T685 T687 T713 T715 S761 T769 T771 T797 T825 T827 K844 T855	Variant Select all A18 A713 A771 A797 A855 C128 F128 G129 I545 I601 I685 I825 K18 K687 K715 K855 L761 N21 R29 R545 R601 R603 R685 R713 R769 R827 T844 Y128	Source Select all Biomuta	Disease [Sample source] Select all DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:184 / bone cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ icgc ] DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:9256 / colorectal cancer [ icgc ] [ cosmic ] [ cosmic ] DOID:184 / bone cancer [ cosmic ] [ cosmic ] DOID:184 / bone cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T18	A18	Biomuta	DOID:10283 / prostate cancer [ cosmic ]
T18	K18	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
K21	N21	Biomuta	DOID:5041 / esophageal cancer [ cosmic ]
K29	R29	Biomuta	DOID:5041 / esophageal cancer [ cosmic, icgc ]
S128	Y128	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
S128	F128	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S128	C128	Biomuta	DOID:1612 / breast cancer [ cosmic, icgc ]
S129	G129	Biomuta	DOID:5041 / esophageal cancer [ cosmic, icgc ]
T545	R545	Biomuta	DOID:8618 / oral cavity cancer [ cosmic ]
T545	I545	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
T601	R601	Biomuta	DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T601	I601	Biomuta	[ cosmic ]
T603	R603	Biomuta	DOID:363 / uterine cancer [ icgc ]
T685	R685	Biomuta	[ cosmic ] DOID:184 / bone cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T685	I685	Biomuta	[ cosmic ] DOID:184 / bone cancer [ cosmic ]
T687	K687	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
T713	A713	Biomuta	[ cosmic ]
T713	R713	Biomuta	DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T715	K715	Biomuta	DOID:1324 / lung cancer [ cosmic ]
S761	L761	Biomuta	DOID:4159 / skin cancer [ cosmic ]
T769	R769	Biomuta	DOID:184 / bone cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
T771	A771	Biomuta	DOID:9256 / colorectal cancer [ icgc ]
T797	A797	Biomuta	DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
T825	I825	Biomuta	DOID:363 / uterine cancer [ icgc ]
T827	R827	Biomuta	DOID:2394 / ovarian cancer [ cosmic, icgc ]
K844	T844	Biomuta	DOID:5041 / esophageal cancer [ cosmic ]
T855	A855	Biomuta	DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T855	K855	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q9NQV7 (PRDM9)

Protein Information

Interactive Sequence View

Q9NQV7 (PRDM9) as Substrate

PTM sites affected in variants