iPTMnet Report for Q9NPB6 (PARD6A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NPB6 / PAR6A_HUMAN
Protein Name Partitioning defective 6 homolog alpha
Gene Name Name: PARD6A
Synonyms:PAR6A;
Organism Homo sapiens (Human)

PRO ID PR:Q9NPB6
DAG View
PRO Name partitioning defective 6 homolog alpha (human)
Definition A partitioning defective 6 homolog alpha that is encoded in the genome of human.
Short Label hPARD6A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NPB6 (PARD6A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K19 Ubiquitination PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S278 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648
S282 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S345 Phosphorylation P37173 (TGFBR2) , P41743 (PRKCI) neXtProt   PhosphoSitePlus   Signor   UniProt 23249950, 15761148, 23186163
Site PTM Type PTM Enzyme Score Source PMID
S278 Phosphorylation HPRD 18691976, 18669648, 15345747
S282 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S108 Phosphorylation HPRD   PhosphoSitePlus 18452278
S277 Phosphorylation HPRD 18691976, 18669648
S281 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S108 F108 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S109 F109 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]