iPTMnet Report Q9NPB6 PARD6A

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9NPB6 / PAR6A_HUMAN
Protein Name	Partitioning defective 6 homolog alpha
Gene Name	Name: PARD6A Synonyms:PAR6A;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9NPB6 DAG View
PRO Name	partitioning defective 6 homolog alpha (human)
Definition	A partitioning defective 6 homolog alpha that is encoded in the genome of human.
Short Label	hPARD6A
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9NPB6 (PARD6A) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K19	Ubiquitination		score1	PhosphoSitePlus
	S100	Phosphorylation		score1	PhosphoSitePlus
	S101	Phosphorylation		score1	PhosphoSitePlus
	S107	Phosphorylation		score1	PhosphoSitePlus
	S109	Phosphorylation		score1	PhosphoSitePlus
	S165	Phosphorylation		score1	PhosphoSitePlus
	S278	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18691976, 18669648
	S282	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	18669648
	S345	Phosphorylation		score4	neXtProt PhosphoSitePlus Signor UniProt	23249950, 15761148, 23186163
	S345	Phosphorylation	P37173 (TGFBR2)	score4	neXtProt Signor	23249950, 15761148
	S345	Phosphorylation	P41743 (PRKCI)	score2	PhosphoSitePlus	23249950

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S278	Phosphorylation		score0	HPRD	18691976, 18669648, 15345747
	S282	Phosphorylation		score0	HPRD	18669648

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S108	Phosphorylation		score2	HPRD PhosphoSitePlus	18452278
	S277	Phosphorylation		score0	HPRD	18691976, 18669648
	S281	Phosphorylation		score0	HPRD	18669648

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S108	F108	Biomuta		DOID:2394 / ovarian cancer [ cosmic, icgc ]
S109	F109	Biomuta		DOID:2394 / ovarian cancer [ cosmic, icgc ]